Computational Biology Exam Sample


1) What is the difference between application and program? Explain in one (1) sentence max. (5
pts)
2) Why would we prefer command line based tool over graphical user interface (GUI) based tool?
Explain in two (2) sentences max. (10 pts)
3) Why is the Basic Local Alignment Search Tool called a heuristic algorithm? Explain in one (1)
sentence max. (5 pts)
4) What is the difference between database search and de novo search in mass spectrometry based
search tools ? Explain in one (1) sentence max. (5 pts)

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